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BIO-DATA
Name
KESHAR KUNJA MOHANTY
Date of Birth
Twelfth June Nineteen hundred sixty three (12-06-1963)
Sex
Female
Marital Status
Married
Corresponding
Address
National JALMA Institute for Leprosy and Other Mycobacterial
Diseases, Dr Miyazaki Marg, Taj Ganj, Agra-282 001
Telephone No.
Fax
E mail
91-562-2331751-55, Extn-222(Lab),255(Res), Mob-9412255180
91-562-2331755
Academic Qualifications
Degree
University
Year
Subject
Division/Topic
Ph.D.
Utkal
1992
Zoology
Characterization of
filarial antigens in
bancroftian filariasis
M.Sc.
Sambal pur
1985
Life Sciences
First Division
B.Sc.
Utkal
1983
Chemistry,
Botany,
Zoology
(Hons)
First Division with
Distinction
Centre for Genetic Engineering and
Department of Microbiology and Cell
Biology, Indian Institute of Sciences,
Bangalore
Research Associate, in CSIR Project at
Institute of Life Sciences, Bhubaneswar,
Odisha
Scientist E, Division of Immunology, National
JALMA Institute for Leprosy and Other
Mycobacterial Diseases (ICMR), Taj Ganj,
Agra- 282 001
Detail of Previous Appointment
Duration
Institute
Particulars of work done
Dec 1986 to
Regional Medical
JRF and SRF
2
May 1992
Research Centre,
Bhubaneswar
(CSIR,NET)(PhD Scholar)Mycobacterial
Genetics, Immunology of filariasis, Sero
surveillance of HIV, routine microbiological
tests.
Sep 1992 to
June 1993
Indian Institute for
Science, Department
of Microbiology and
Cell Biology, Centre
for Genetic
Engineering,
Bangalore
Research Associate,
Molecular biology of
mycobacteriaophage
June 1993
Nov 1994
Institute of Life-
Sciences,
Bhubaneswar,Odisha
Research Associate,
CSIR project
Involvement of ADP ribosylation in oral cancer,
Study of eukaryotic chromatin structure.
Jan 1995 to
2000
National JALMA
Institute for Leprosy
and Other
Mycobacterial
Diseases,(ICMR),
Taj-Gang,Agra
Research Officer,
Immunology of Leprosy, Antigenic mimicry
between host and mycobacterial components.
Jan 2001 to
2006
National JALMA
Institute for Leprosy
and Other
Mycobacterial
Diseases,(ICMR),
Taj-Gang,Agra
Senior Research Officer/Scientist C,
Immunology and Immunogenetics of Leprosy
and Tuberculosis, Antigenic mimicry between
host and mycobacterial components
Jan 2006 to
August 2011
National JALMA
Institute for Leprosy
and Other
Mycobacterial
Senior Research Officer,Scientist-D
Immunology and Immunogenetics of Leprosy
and Tuberculosis,Antigenic mimicry between
host and mycobacterial components
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Diseases,(ICMR),
Taj-Gang,Agra
September
2011
onwards
National JALMA
Institute for Leprosy
and Other
Mycobacterial
Diseases,(ICMR),
Taj-Gang,Agra
Scientist E,
Immunology and Immunogenetics of Leprosy,
Tuberculosis and HIV
JRF-National Entrance Test(NET) 1987 conducted by
CSIR-UGC
Dr. Manu Bhai Patel award for best poster presentation
during 29
th
IADVL Conference held in Agra in 2001.
Best poster presentation in the 3
rd
Convention of
Society for Immunology and Immunopathology held
in Agra (2004).
Immunology foundation award for best poster
presentation during 25
th
Biennial Conference of the
Indian Association of Leprologists held in Kanpur in
2007.
Indian Immunology Society(Past Executive Member)
Indian Association of Leprologists
Presently, Vice President- Indian Association of
Leprologists
Research Experience:
Specialized fields (Present)
Understanding host parasite interactions by studying host immunogenetics -
TLRs / NOD 2 polymorphism in mycobacterial diseases (Leprosy, Tuberculosis
and HIV), TLR s /NOD 2 expression and its role in immune response to various
mycobacterial antigens.
Understanding immunopathogenesis of leprosy reactions –
Immune response to various stress proteins of M leprae, nitric oxide metabolism
during reactions and their role as immunological markers for reactions.
Understanding local immunity in leprosy lesions –
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Local antibody synthesis, cytokine secretion and characterization of lesional cells
by immunohistology.
Specialized fields (Past)
Understanding Mycobacterial genetics by producing auxotrophic mutants of
Mycobacteria and characterization by syntrophism. Analysis of cloned
Mycobacteriophage DNA by various molecular methods. Characterization of
filarial antigens in bancroftian filariasis. Analysis of Eukaryotic chromatin
structure.
Teaching Experience
Teaching
Lectures in Immunology were delivered to M.Sc.(Bio-Chemistry,
Biotechnology and Microbiology) students of Dr.B.R.Ambedkar
University,Agra from 1997 to 2004.
Guidance for Ph.D. Students- Two scholars were awarded with PhD in
BioTechnology from Dr B.R.Ambedkar University and two
scholars have submitted their thesis one in Dr B.R.Ambedkar
University, Agra in Biochemistry and One in Jiwajee University,
Gwalior in faculty of Biotechnology. One student is registered in
Jiwajee University, Gwalior in Biotechnology. Three more students
have applied for Ph.D. registration.
M.Sc. Dissertation and summer training
Supervised more than 50 M.Sc. students from various Universities for
project work for their dissertations.
Training was imparted on various techniques of molecular Immunology to
graduate and post graduate summer trainees from various Universities.
Examiner
Acted as external examiner for practical examination for B.Sc and
and Dissertation theses viva for M.Sc students of various colleges
under Dr B.R.Ambedkar University, Agra, Ser question papers and
evaluated answer sheets for M.Sc students
Invited Lecture-
Delivered Invited lecture in Jiwajee University Gwalior during
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International Women Conference in 2013 and 2015.
Delivered invited lecture in Post Graduate Institute of Medical
Education and Research, Chandigarh, during Biannual National
Conference of Indian Association of Leprologist in 2013.
Delivered invited lecture in CME in Institute of Medical Sciences,
Banaras Hindu University, Varanasi in 2015.
Acted as Pannelist during Mid term Conference at Gandhi Medical
Institute, Hyderabad in 2015
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PUBLICATIONS
1. Ekata Sinha, Sanjay K Biswas, Mayank Mittal, Bharat Bajaj,Vandana Singh,
Nidhi Arela, Vishwa M Katoch, Keshar K Mohanty. Toll-like Receptor 1
743A>G, 1805 T>G & Toll-like Receptor 6 745 C>T gene polymorphism and
tuberculosis: A case control study of north Indian population from Agra(India).
Human Immunology (2014):75 880–886.
2. Itu Singh, Asha Ram Yadav, Keshar Kunja Mohanty, Kiran Katoch, Prashant
Sharma, Bishal Mishra, Deepa Bisht, U.D.Gupta, Utpal Sengupta. Molecular
mimicry between Mycobacterium leprae proteins(50S ribosomal protein L2 and
Lysyl-tRNA synthetase) and myelin basic protein: A possible mechanism of nerve
damage in leprosy. Microbes and Infection xx(2015)1-11.
3. V. Singh, R. Gaur, M. Mittal, S. K. Biswas, R. Das, B. K. Girdhar, B. Bajaj,V. M.
Katoch, A. Kumar & K. K. Mohanty. Absence of nucleotide-binding
oligomerization domain-containing protein 2 variants in patients with leprosy and
tuberculosis, International Journal of Immunogenetics, 2012, 39, 353–356.
4. Itu Singh, Asha Ram Yadav, Keshar Kunja Mohanty, Kiran Katoch, Deepa
Bisht, Prashant Sharma ,Bhawna Sharma,U. D. Gupta, Utpal Sengupta Molecular
mimicry between HSP 65 of M. leprae and cytokeratin 10 of the host keratin;
Role in pathogenesis of leprosy. Cellular Immunology 2012;(278)1-2:63-75
5. K.K.Mohanty, M.Gupta, B.K.Girdhar, A.Girdhar, J.K.Chakma and U. Sengupta:
Increased level of urinary nitric oxide metabolites in leprosy patients during Type
2 reactions and decreased after antireactional therapy. Lepr Rev(2007) 78,386-
390.
6. A.M.Iyer, K.K.Mohanty, D.V.Egmond, K.Katoch, W.R.Faber, P.K.Das and
U.Sengupta: Leprosy–specific B-cells within cellular infiltrates in active leprosy
lesions. Human Pathology (2007) 38, 1065-1073.
7. K.K.Mohanty, Beenu Joshi, K.Katoch and U Sengupta: Leprosy Reactions:
Humoral and cellular responses to M leprae, 65kDa, 28kDa and 18kDa antigens.
Int J. Lepr (2004), 72: p149-158.
8. B.Joshi, B.K.Girdhar., K.K.Mohanty, M.K.Beuria., A.Girdhar and U. Sengupta:
Immunological profile of long term treated smear negative (LTTSN) lepromatous
patients to M.leprae antigens, Int J. Lepr (2001) 69 (3) 195-203.
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9. M.K.Beuria , Keshar K.Mohanty, Kiran Katoch and U. Sengupta: Determination
of IgG subclasses Against Lipoarabinomannan in the Leprosy Spectrum and
Reactions, Int J. Lepr (1999),67,No 4, 422-428.
10. M.K.Beuria, Om Parkash, B.Joshi, K.K.Mohanty, K.Katoch & U.Sengupta:
Levels of IgG subclasses in active and inactive cases in the disease spectrum of
leprosy .Int Arch Allergy Immunol. (1998)115: 61-66.
11. V.R.Subramanyam, B.B.Pal and K.K.Mohanty: Inducibility and stability of
auxotrophic mutations in Mycobacterium fortuitum, M smegmatis and M.vaccae.
Letters in applied Microbiology,8 :p161-164,1989.
12. V.R.Subramanyam and K.K.Mohanty: Partial characterization of Mycobacterium
fortuitum and Mycobacterium smegmatis auxotrophs by syntrophism using
Bacillus subtilis.Journal of General Microbiology, 135: p2651-2654, 1989.
13. M Sharma, M Lavania, P Sharma, KK Mohanty, K Katoch, U Sengupta .
Analysis of immune status of leprosy patients of Ghatampur field area after
completion of chemotherapy by using immunological markers
Journal of Immunology and Immunopathology 6 (supp1), 141-142.2004
14. Shankar, B Joshi, KK Mohanty, U Sengupta Evaluation of cell mediated immune
response of tuberculosis patients and their healthy contacts to Mycobacterium
tuberculosis antigen. Journal of Immunology and Immunopathology 6 (supp1), 66-
67.2004
15. KK Mohanty, S Rai, K Katoch, R Dayal, U Sengupta. Evaluation of cell mediated
immune response of tuberculosis patients and their healthy contacts to
Mycobacterium tuberculosis antigen. Journal of Immunology and
Immunopathology 6 (supp1), 118-119.2004
16. Mayank Mittal , Sanjay Kumar Biswas , Vandana Singh , Nidhi Arela , Vishwa
Mohan Katoch , Ram Das , Virendra Singh Yadav , Bharat Bajaj and Keshar
Kunja Mohanty. Association of Toll like receptor 2 and 9 Gene Variants with
Pulmonary 2 Tuberculosis- Exploration in a Northern Indian
Population.Submitted to PLoS One.
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